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REBUILD Bundle

$180.00 USD $260.00 USD -30%
Third-party tested COA available ≥99% purity

The REBUILD Bundle is a three-vial tissue-repair research stack: the BPC-157 / TB-500 blend (5 mg + 5 mg), a full BPC-157 10 mg vial and GHK-Cu 50 mg — at 10% off the individual vial prices.

BPC-157 is a stable gastric pentadecapeptide studied in tendon-healing models, where it promoted fibroblast outgrowth, survival and migration[1]. TB-500 is synthetic full-length thymosin beta-4, an actin-regulating peptide that promoted cell migration and repair signalling in preclinical studies[6]. GHK-Cu is the copper complex of a naturally occurring tripeptide studied as a modulator of multiple cellular pathways in skin-regeneration research[7].

Each vial is supplied as a lyophilized powder for reconstitution, and each compound has its own lot-specific third-party certificate of analysis, available on request. Findings above come from preclinical (animal and cell-based) research on these molecules and are provided as scientific reference for laboratory research only.

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FormLyophilized powder
Purity≥ 99% (HPLC / MS)
TestingThird-party, every batch
ShippingSame-day from the USA
ClassificationResearch Use Only

Need reconstitution solution? Don’t forget to add Bacteriostatic Water before checkout.

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Other research compounds in stock

All research peptides in stock  ·  Reconstitution calculator  ·  Certificates of Analysis

Research stack REBUILD Bundle  =  BPC-157 / TB-500 blend 5/5 mg  +  BPC-157 10 mg  +  GHK-Cu 50 mg

Tissue-Repair Research Stack

Three Vials, One Research Focus

The REBUILD Bundle concentrates on a single research theme: tissue repair. The BPC-157 / TB-500 blend pairs two repair-oriented peptides in one vial, backed by a second full-dose BPC-157 vial — a pentadecapeptide documented in tendon-healing models[1] and in angiogenesis models, with pro-angiogenic activity associated with VEGFR2 activation[3]. GHK-Cu adds the dermatological angle: the copper complex of a naturally occurring tripeptide studied as a modulator of multiple cellular pathways in skin-regeneration research[7].

  • One focused research theme across three vials
  • BPC-157 — tendon-healing and angiogenesis models
  • TB-500 — full-length thymosin beta-4 (43 aa)
  • GHK-Cu — copper tripeptide, skin and remodelling research
  • Lot-specific third-party COA for each compound
Rebuild Bundle three-vial tissue-repair research diagram

Inside the Bundle

What's in the Stack

The bundle ships as three separate lyophilized vials: the BPC-157 / TB-500 blend (5 mg + 5 mg), BPC-157 10 mg and GHK-Cu 50 mg. In preclinical models, BPC-157 has been studied on fibroblast migration[1], while thymosin beta-4 — supplied as TB-500 — has been characterised in actin dynamics[5]. GHK-Cu adds a copper-peptide mechanism studied in skin and connective-tissue research[7].

  • BPC-157 / TB-500 — 5 mg + 5 mg blend vial
  • BPC-157 — 10 mg lyophilized vial
  • GHK-Cu — 50 mg lyophilized vial
  • Peptide repair signalling + copper-peptide chemistry
  • 10% saving versus buying the three vials separately
Rebuild Bundle research vials

Research Applications

Areas of Scientific Investigation

Each compound has been studied separately in repair-oriented research: in a rat model, BPC-157 accelerated healing of the transected Achilles tendon[2]; thymosin beta-4 — the molecule supplied as TB-500 — activated integrin-linked kinase and promoted cardiac cell migration, survival and repair[6]; and GHK-Cu transiently improved healing outcome in a rat model of ACL reconstruction[8]. No published study evaluates the three vials in combination; researchers using them side by side are combining independent lines of evidence.

  • Tendon, ligament and muscle injury models
  • Wound-healing and angiogenesis assays
  • Skin-regeneration and remodelling research
  • Actin dynamics and cytoskeletal research
Peptide research laboratory
Research Overview

Understanding the Rebuild Stack: Mechanism of Action

BPC-157 is a 15-amino-acid fragment of the Body Protection Compound found in gastric juice. In preclinical models it has been reported to promote tissue-repair signalling through several converging mechanisms: promotion of tendon-fibroblast outgrowth and migration, likely via the FAK–paxillin pathway[1], accelerated healing of transected tendon in a rat study[2], pro-angiogenic activity associated with VEGFR2 activation[3], and a documented relationship with the nitric-oxide system[4]. The bundle carries it twice: inside the blend and as a full 10 mg vial.

TB-500, the second half of the blend, is synthetic full-length thymosin beta-4 (43 amino acids), identified as a principal G-actin-sequestering peptide. Thymosin beta-4 binds monomeric G-actin and regulates its polymerisation[5] — the machinery cells use to move. In a 2004 Nature study, thymosin beta-4 activated integrin-linked kinase and promoted cardiac cell migration and survival after injury[6].

GHK-Cu is the copper complex of glycyl-L-histidyl-L-lysine, a tripeptide naturally present in human plasma. It has been studied as a modulator of multiple cellular pathways in skin regeneration — collagen synthesis, remodelling and antioxidant defence[7] — and, in a rat model of ACL reconstruction, transiently improved healing outcome[8].

Together, the three vials give researchers a repair-focused toolkit: peptide-driven repair signalling (BPC-157, thymosin beta-4) alongside copper-peptide chemistry (GHK-Cu). Each pathway is supported by its own line of preclinical evidence; no published study evaluates the combination itself. These materials are supplied strictly for laboratory research use.

Scientific Literature

  1. Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol (1985). 2011;110(3):774-80.
  2. Staresinic M, Sebecic B, Patrlj L, et al. Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth. J Orthop Res. 2003;21(6):976-83.
  3. Hsieh MJ, Liu HT, Wang CN, et al. Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. J Mol Med (Berl). 2017;95(3):323-333.
  4. Sikiric P, Seiwerth S, Rucman R, et al. Stable gastric pentadecapeptide BPC 157-NO-system relation. Curr Pharm Des. 2014;20(7):1126-35.
  5. Safer D, Elzinga M, Nachmias VT. Thymosin beta 4 and Fx, an actin-sequestering peptide, are indistinguishable. J Biol Chem. 1991;266(7):4029-32.
  6. Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D. Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature. 2004;432(7016):466-72.
  7. Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2015;2015:648108.
  8. Fu SC, Cheuk YC, Chiu WY, Yung SH, Rolf CG, Chan KM. Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction. J Orthop Res. 2015;33(7):1024-1033.
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  • REBUILD Bundle

    REBUILD Bundle

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