REBORN Bundle
The REBORN Bundle is a three-vial multi-angle research stack: Retatrutide 12 mg, GHK-Cu 50 mg and Melanotan II 10 mg — metabolic, skin and melanocortin research tools, at 10% off the individual vial prices.
Retatrutide is a triple GIP, GLP-1 and glucagon receptor agonist that produced substantial, dose-dependent weight reduction in a phase 2 trial[1]. GHK-Cu is the copper complex of a naturally occurring tripeptide, studied in skin-regeneration research[3]. Melanotan II is a synthetic melanocortin-receptor agonist used as a pharmacological tool in melanocortin research[5].
Each vial is supplied as a lyophilized powder for reconstitution, and each compound has its own lot-specific third-party certificate of analysis, available on request. Findings above come from preclinical and clinical research on these molecules and are provided as scientific reference for laboratory research only.
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Multi-Angle Research Stack
Three Vials, Three Research Angles
The REBORN Bundle covers three distinct research angles in one set. Retatrutide is a triple GIP, GLP-1 and glucagon receptor agonist, taken from discovery to clinical proof of concept in the published literature[2]. GHK-Cu is the copper complex of a naturally occurring tripeptide, studied as a modulator of multiple cellular pathways in skin-regeneration research[3]. Melanotan II is a synthetic melanocortin-receptor agonist used as a pharmacological tool across melanocortin research[5].
- Metabolic, skin and melanocortin research in one set
- Retatrutide — triple GIP/GLP-1/glucagon agonist
- GHK-Cu — copper tripeptide, skin and remodelling research
- Melanotan II — melanocortin-receptor research peptide
- Lot-specific third-party COA for each compound
Inside the Bundle
What's in the Stack
The bundle ships as three separate lyophilized vials: Retatrutide 12 mg, GHK-Cu 50 mg and Melanotan II 10 mg. Each works through a different pharmacological route: retatrutide engages three metabolic receptors at once — in a phase 2 trial it produced substantial, dose-dependent weight reduction in adults with obesity[1] — while GHK-Cu works through copper-peptide chemistry[3] and Melanotan II through melanocortin receptors[5].
- Retatrutide — 12 mg lyophilized vial
- GHK-Cu — 50 mg lyophilized vial
- Melanotan II — 10 mg lyophilized vial
- Incretin + copper-peptide + melanocortin coverage
- 10% saving versus buying the three vials separately
Research Applications
Areas of Scientific Investigation
Each compound carries its own line of evidence: retatrutide improved glycaemic control and reduced body weight in a randomised phase 2 trial in type 2 diabetes[6]; GHK-Cu transiently improved healing outcome in a rat model of ACL reconstruction[4]; and melanocortin-receptor agonism was studied in rodent appetite models with Melanotan II[7]. No published study evaluates the three compounds in combination; researchers using them side by side are combining independent lines of evidence.
- Incretin and glucagon-receptor signalling research
- Skin-regeneration and remodelling research
- Melanocortin-receptor and pigmentation research
- Appetite-signalling and energy-balance models
Understanding the Reborn Stack: Mechanism of Action
Retatrutide is a single molecule engaging three receptors: GIP, GLP-1 and glucagon. Its pharmacology was taken from discovery to clinical proof of concept in 2022[2]; in a phase 2 trial it produced substantial, dose-dependent weight reduction in adults with obesity[1], and it improved glycaemic control in a randomised phase 2 trial in type 2 diabetes[6].
GHK-Cu is the copper complex of glycyl-L-histidyl-L-lysine, a tripeptide naturally present in human plasma. It has been studied as a modulator of multiple cellular pathways in skin regeneration — collagen synthesis, remodelling and antioxidant defence[3] — and, in a rat model of ACL reconstruction, transiently improved healing outcome[4].
Melanotan II is a cyclic synthetic analogue of alpha-melanocyte-stimulating hormone that activates melanocortin receptors. It is used as a pharmacological scaffold in melanocortin-receptor research[5], and in rodent models melanocortin-receptor agonism with Melanotan II decreased appetitive responding for food[7].
Together, the three vials give researchers three independent pharmacological axes: incretin/glucagon receptor signalling (retatrutide), copper-peptide chemistry (GHK-Cu) and melanocortin receptor signalling (Melanotan II). Each is supported by its own line of evidence; no published study evaluates the combination itself. These materials are supplied strictly for laboratory research use.
Scientific Literature
- Jastreboff AM, Kaplan LM, Frias JP, et al. Triple-hormone-receptor agonist retatrutide for obesity. N Engl J Med. 2023;389(6):514-526.
- Coskun T, Urva S, Roell WC, et al. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: from discovery to clinical proof of concept. Cell Metab. 2022;34(9):1234-1247.e9.
- Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2015;2015:648108.
- Fu SC, Cheuk YC, Chiu WY, Yung SH, Rolf CG, Chan KM. Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction. J Orthop Res. 2015;33(7):1024-1033.
- Tomassi S, Dimmito MP, Cai M, et al. CLIPSing Melanotan-II to Discover Multiple Functionally Selective hMCR Agonists. J Med Chem. 2022;65(5):4007-4017.
- Rosenstock J, Frias JP, Jastreboff AM, et al. Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes. Lancet. 2023;402(10401):529-544.
- Eliason NL, Martin L, Low MJ, Sharpe AL. Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food. Neuropeptides. 2022;96:102289.
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REBORN Bundle
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$234.00$420.00
- ≥99%96%
- 3 vials3 vials
- Free 2-Day Shipping3-10 Business Day
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