{"product":{"id":9304105812130,"title":"KPV – 5mg","body_html":"\u003cdiv class=\"plp-desc-rt\"\u003e\n\u003cstyle\u003e\n.plp-desc-rt{font-family:var(--font-body-family,Helvetica,Arial,sans-serif);color:rgba(18,18,18,.7)}\n.plp-desc-rt p{margin:0 0 15px;font-size:15.5px;font-weight:400;line-height:1.7}\n.plp-desc-rt strong{color:#0e2a44;font-weight:600}\n.plp-desc-rt em{color:rgba(18,18,18,.5)}\n.plp-desc-rt sup{line-height:0}\n.plp-desc-rt sup a{font-size:11px;font-weight:600;color:#2279be;text-decoration:none;padding:0 1px}\n.plp-desc-rt sup a:hover{color:#0e2a44}\n\u003c\/style\u003e\n\u003cp\u003e\u003cstrong\u003eKPV\u003c\/strong\u003e is a synthetic tripeptide composed of lysine, proline and valine, corresponding to residues 11-13 at the C-terminus of alpha-melanocyte-stimulating hormone. It is studied as a structurally minimal fragment of that hormone, which is precisely what makes it useful as a laboratory tool: it allows investigators to ask which properties of the parent sequence persist once the rest of the molecule is removed.\u003c\/p\u003e\n\u003cp\u003eThe published literature on KPV is concentrated in gastrointestinal inflammation research. The reported anti-inflammatory activity is described as independent of the melanocortin receptor MC1R, which distinguishes the fragment from the parent hormone. Cellular entry is described as PepT1-mediated, with the di- and tripeptide transporter of intestinal epithelial and immune cells carrying the intact peptide into the cell. In experimental colitis models, the reported readouts include pro-inflammatory cytokine expression and NF-kB pathway activation.\u003c\/p\u003e\n\u003cp\u003eA second research axis is delivery. Nanoparticle and hydrogel carriers have been used to concentrate the tripeptide at the colon rather than distribute it systemically. A related line of work examines the PepT1 transporter in colitis-associated tumorigenesis models, which is why the transporter itself recurs as a variable in this field.\u003c\/p\u003e\n\u003cp\u003eThe evidence base is in vitro and rodent; no clinical data are presented, and no human dosing or administration route is described anywhere in this material. This product is supplied for laboratory research use only and is not intended for human or veterinary use, diagnostic procedures, or any therapeutic application.\u003c\/p\u003e\n\u003c\/div\u003e","vendor":"Prime Lab Peptides","product_type":"","created_at":"2026-08-17T08:31:33-04:00","handle":"kpv-5mg","updated_at":"2026-10-01T15:23:27-04:00","published_at":"2026-08-17T09:20:46-04:00","template_suffix":"kpv","published_scope":"global","tags":"","variants":[{"id":47540251099298,"product_id":9304105812130,"title":"Default Title","price":"35.00","sku":"KPV5","position":1,"compare_at_price":"47.50","fulfillment_service":"manual","inventory_management":"shopify","option1":"Default Title","option2":null,"option3":null,"created_at":"2026-08-17T08:31:33-04:00","updated_at":"2026-10-01T15:23:27-04:00","taxable":true,"barcode":"","grams":0,"image_id":null,"weight":0.0,"weight_unit":"lb","requires_shipping":true,"quantity_rule":{"min":1,"max":null,"increment":1},"price_currency":"USD","compare_at_price_currency":"USD","quantity_price_breaks":[]}],"options":[{"id":null,"product_id":9304105812130,"name":"Title","position":1,"values":["Default Title"]}],"images":[{"id":36908913066146,"product_id":9304105812130,"position":1,"created_at":"2026-08-17T08:31:33-04:00","updated_at":"2026-10-01T15:23:27-04:00","alt":"KPV – 5mg","width":1600,"height":1600,"src":"https:\/\/primelabpeptides.com\/wp-content\/themes\/primelab\/media.php?f=files\/primelab-kpv-5mg.webp","variant_ids":[]},{"id":37268723105954,"product_id":9304105812130,"position":2,"created_at":"2026-08-17T08:31:33-04:00","updated_at":"2026-10-01T15:23:27-04:00","alt":"Certificate of Analysis - KPV 5mg - lot 068417253KPV - 99.51% purity - Freedom Diagnostics","width":2550,"height":3300,"src":"https:\/\/primelabpeptides.com\/wp-content\/themes\/primelab\/media.php?f=files\/primelab-coa-kpv-5mg-lot-068417253KPV.webp","variant_ids":[]}],"image":{"id":36908913066146,"product_id":9304105812130,"position":1,"created_at":"2026-08-17T08:31:33-04:00","updated_at":"2026-10-01T15:23:27-04:00","alt":"KPV – 5mg","width":1600,"height":1600,"src":"https:\/\/primelabpeptides.com\/wp-content\/themes\/primelab\/media.php?f=files\/primelab-kpv-5mg.webp","variant_ids":[]}}}